Flow Assignment and Processing on a Distributed Edge Computing Platform

The evolution of telecommunication networks toward the fifth generation of mobile services (5G), along with the increasing presence of cloud-native applications, and the development of Cloud and Mobile Edge Computing (MEC) paradigms, have opened up new opportunities for the monitoring and management of logistics and transportation. We address the case of distributed streaming platforms with multiple message brokers to develop an optimization model for the real-time assignment and load balancing of event streaming generated data traffic among Edge Computing facilities. The performance indicator function to be optimised is derived by adopting queuing models with different granularity (packet- and flow-level) that are suitably combined. A specific use case concerning a logistics application is considered and numerical results are provided to show the effectiveness of the optimisation procedure, also in comparison to a “static” assignment proportional to the processing speed of the brokers

A critical review of the mechanisms involved in the occurrence of growth-related abnormalities affecting broiler chicken breast muscles

In the past decade, the poultry industry has faced the occurrence of growth-related muscular abnormalities that mainly affect, with a high incidence rate, the Pectoralis major of the fast-growing genotypes selected for their production performances (high growth rate and breast yield). These myopathies are termed as White Striping, Wooden Breast, and Spaghetti Meat and exhibit distinctive phenotypes. A spatiotemporal distribution has been demonstrated for these disorders as in the early stage they primarily affect the superficial area in the cranial portion of the muscle and, as the birds grow older, involve the entire tissue. Aside from their distinctive phenotypes, these myopathies share common histological features. Thus, it might be speculated that common causative mechanisms might be responsible for the physiological and structural perturbations in the muscle associated with these conditions and might underpin their occurrence. The present review paper aims to represent a critical survey of the outcomes of all the histologic and ultrastructural observations carried out on White Striping, Wooden Breast, and Spaghetti Meat affected muscles. Our analysis has been performed by combining these outcomes with the findings of the genetic studies, trying to identify possible initial causative mechanisms triggering the onset and the time-series of the events ultimately resulting in the development and progression of the growth-related myopathies currently affecting broilers Pectoralis major muscles. Several evidences support the hypothesis that sarcoplasmic reticulum stress, primarily induced an accumulation of misfolded proteins (but also driven by other factors including altered calcium homeostasis and accumulation of fatty acids), may be responsible for the onset of these growth-related myopathies in broilers. At the same time, the development of hypoxic conditions, as a direct consequence of an inadequate vascularization, triggers a time-series sequence of events (i.e., phlebitis, oxidative stress, etc.) resulting in the activation of response mechanisms (i.e., modifications in the energetic metabolism, inflammation, degeneration, and regeneration) which are all strictly related to the progression of these myopathic disorders

Satellite networking integration in the 5G ecosystem: Research trends and open challenges

The envisioned 5G ecosystem will be composed of heterogeneous networks based on different technologies and communication means, including satellite communication networks. The latter can help increase the capabilities of terrestrial networks, especially in terms of higher coverage, reliability, and availability, contributing to the achievement of some of the 5G KPIs. However, technological changes are not immediate. Many current satellite communication networks are based on proprietary hardware, which hinders the integration with future 5G terrestrial networks as well as the adoption of new protocols and algorithms. On the other hand, the two main paradigms that are emerging in the networking scenario \u2014 software defined networking (SDN) and network functions virtualization \u2014 can change this perspective. In this respect, this article presents first an overview of the main research works in the field of SDN satellite networks in order to understand the already proposed solutions. Then some open challenges are described in light of the network slicing concept by 5G virtualization, along with a possible roadmap including different network virtualization levels. The remaining unsolved problems are related to the development and deployment of a complete integration of satellite components in the 5G ecosystem

Small satellites and CubeSats: survey of structures, architectures, and protocols

The space environment is still challenging but is becoming more and more attractive for an increasing number of entities. In the second half of the 20th century, a huge amount of funds was required to build satellites and gain access to space. Nowadays, it is no longer so. The advancement of technologies allows producing very small hardware components able to survive the strict conditions of the outer space. Consequently, small satellites can be designed for a wide set of missions keeping low design times, production costs, and deployment costs. One widely used type of small satellite is the CubeSat, whose different aspects are surveyed in the following: mission goals, hardware subsystems and components, possible network topologies, channel models, and suitable communication protocols. We also show some future challenges related to the employment of CubeSat networks

Solitary fibrous tumor of the pleura: surgery and clinical course in 18 cases

Solitary fibrous tumors of the pleura are very rare neoplasms that can sometimes present with malignant features. Between 1984 and 2007, 18 cases were treated in our institution. There were 7 men and 11 women, with a median age of 56 years (range, 33-77 years). All patients underwent surgical treatment. Except for one case with hemangiopericytic features, all tumors were histologically the fibrous type of pleural mesothelioma. Resections were radical and there were no recurrences. There was no perioperative mortality. The outcome was excellent, and all patients have been followed up continuously. Survival rates at 3, 5, and 10 years were calculated as 86.7%, 75%, and 66.7%. One patient died after 18 months (malignant type of solitary fibrous tumor), and 2 died of unrelated disease after 24 and 53 months. Surgery is the treatment of choice, and careful long-term clinical follow-up is required

Multi-site Resource Allocation in a QoS-Aware 5G Infrastructure

Network softwarization has paved the way for 5G technologies, and a wide-range of (radically new) verticals. As the telecommunications infrastructure evolves into a sort of distributed datacenter, multiple tenants such as vertical industries and network service providers share its aggregate pool of resources (e.g., networking, computing, etc.) in a layered \u201das-a-Service\u201d approach exposed as slice abstractions. The challenge remains in the coordination of various stakeholders\u2019 assets in realizing end-to-end network slices and supporting the multi-site deployment and chaining of the micro-service components needed to implement cloud-native vertical applications (vApps). In this context, particular care must be taken to ensure that the required resources are identified, made available and managed in a way that satisfies the vApp requirements, allows for a fair share of resources and has a reasonable impact on the overall vApp deployment time. With these challenges in mind, this paper presents the Resource Selection Optimizer (RSO)-a software-service in the MATILDA Operations Support System (OSS), whose main goal is to select the most appropriate network and computing resources (according to some criterion) among a list of options provided by the Wide-area Infrastructure Manager (WIM). It consists of three submodules that respectively handle: (i) the aggregation of vApp components based on affinities, (ii) the forecasting of (micro-) datacenter resources utilization, (iii) and the multi-site placement of the (aggregated) vApp micro-service components. The RSO\u2019s performance is mainly evaluated in terms of the execution times of its submodules while varying their respective input parameters, and additionally, three selection policies are also compared. Experimental results aim to highlight the RSO behavior in both execution times and deployment costs, as well as the RSO interactions with other OSS submodules and network platform components, not only for multi-site vApp deployment but also for other network/services management operations

Typical and atypical pulmonary carcinoids: our institutional experience

Pulmonary carcinoids are rare malignant neoplasms, accounting for 2-5% of all lung tumors, with an approximate annual incidence of 2.3-2.8 cases per million of the population. We relate our experience of 54 patients (21 male, 33 female, mean age 53+/-15 years) treated between July 1986 and April 2006. All the patients underwent preoperative fibrobronchoscopy: preoperative diagnosis was made in 28 patients (52%). Surgical treatment consisted of: 31 standard lobectomies, 6 pneumonectomies, 5 bilobectomies, 2 sleeve lobectomies, 2 anatomic segmentectomies, 6 wedge resections; two patients were managed with sleeve bronchial procedure of the left main bronchus without lung resection. Fifty-four patients were followed with a mean time of observation of 67 months: 6 (11%) deaths occurred, at a mean period of 49 months after surgery; there were no postoperative deaths. Overall, 5-year survival was 91%, 10 years 83%: 5-year survival was 91% for typical carcoinoids (TC) vs. 88% for atypical (AC), 10 years 91% for TC and 44% for AC (significant value, P=0.0487). Carcinoid tumors are a distinct group of neuroendocrine tumors with a good prognosis in most cases. Surgery currently represents the best treatment with good results at mid- and long-term survival, according to an acceptable risk

Use of coagulant spray glue (Glubran 2) for aerostatic purposes in pulmonary parenchyma resections in pigs: a preliminary study

BACKGROUND: The aim of our study was to test the aerostatic validity of a cyan-acrylic glue (Glubran 2), applied by means of a spray catheter, on an experimental pig model. MATERIALS AND METHODS: 15 young pigs were divided into three study groups of 5 based on surgical techniques: (1) atypical pulmonary resection with mechanical suturing and reinforcement with continuous suturing; (2) resection of the pulmonary parenchyma with a cold scalpel, followed by local application of Glubran 2; (3) atypical pulmonary resection with mechanical suturing followed by application of Glubran 2. RESULTS: The mean aerostasis time was calculated at 3.5 +/- 1.26 s. The histopathological analysis did not show any particular differences when comparing the effects of the treatments carried out with Glubran 2 spray glue and the standard treatments. No statistically significant differences were recorded in the short- and medium-term survival of pigs treated with Glubran 2 compared with the respective control groups. CONCLUSIONS: The application of Glubran 2 spray on wounds caused by pulmonary resections in pigs proved to have a rapid and effective influence for the purposes of aerostasis without significant differences in air losses and survivals